Publications

Metallophilic interactions

45. The energetic significance of metallophilic interactions

Q. Zheng, S. Borsley, G. S. Nichol, F. Duarte, S. L. Cockroft*. Angew. Chem. Int. Ed., DOI:10.1002/anie.201904207 (2019). Citations

- Featured as a hot paper in Angew. Chem.

Click

44. Synthetically diversified protein nanopores: Resolving click reaction mechanisms

M. M. Haugland, S. Borsley, D. F. Cairns-Gibson, A. Elmi, S. L. Cockroft*. ACS Nano, 13, 4101–4110 (2019). Citations

Cages 43. Electrostatic forces in field-perturbed equilibria: nanopore analysis of cage complexes
S. Borsley, M. M. Haugland, S. Oldknow, J. A. Cooper, M. J. Burke, A. Scott, W. Grantham, J. Vallejo, E. K. Brechin, P. J. Lusby,* S. L. Cockroft*. Chem (Cell Press), 5 1275-1292 (2019). Citations

- Featured as a Preview in Chem

Simultaneous G-quadruplex DNA logic

42. Simultaneous G-quadruplex DNA logic

A. Bader, S. L. Cockroft*. Chem. Eur. J., 24, 4820-4824 (2018). Citations

Nanopore detection of single-molecule binding within a metallosupramolecular cage

41. Nanopore detection of single-molecule binding within a metallosupramolecular cage

S. Borsley, J. A. Cooper, P. J. Lusby, S. L. Cockroft*. Chem. Eur. J., 24, 4542-4546 (2018). Citations

An RNA-dependent mechanism for transient expression of bacterial translocation filaments
40. An RNA-dependent mechanism for transient expression of bacterial translocation filaments

D. Wang, S. P. McAteer, A. B. Wawszczyk, C. D. Russell, A. Tahoun, A. Elmi, S. L. Cockroft, D. Tollervey, S. Granneman, J. J. Tree*, D. L. Gally*. Nucleic Acids Res., 46, 3366-3381 (2018). Citations

membrane activity of peptaibol-mimetic foldamers
38. The role of terminal functionality in the membrane and antibacterial activity of peptaibol-mimetic Aib foldamers

C. Adam, A. D. Peters, M. G. Lizio, G. F. S. Whitehead, J. A. Cooper, S. L. Cockroft, J. Clayden*, S. J. Webb*. Chem. Eur. J., 24, 2249-2256 (2018). Citations

-Featured as a Hot Paper in Chem. Eur. J.

Chalcogen bonding

37. The origin of chalcogen-bonding interactions

D. J. Pascoe, K. B. Ling, S. L. Cockroft*. J. Am. Chem. Soc., 139, 15160-15167 (2017). Citations

Anion Recognition

36. Screening solvent effects in anion recognition

S. L. Cockroft*. Chem (Cell Press), 3, 383-384 (2017). Citations

High-throughput RNA structure probing
35. High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast

E. Burlacu, F. Lackmann, L.-C. Aguilar, S. Belikov, R. van Nues, C. Trahan, R. D. Hector, N. Dominelli-Whiteley, S. L. Cockroft, L. Wieslander, M, Oeffinger, S. Granneman*. Nature Commun., 8, Article Number 714 (2017). Citations

modification of FabH
34. Structural evidence for the covalent modification of FabH by 4,5-dichloro-1,2-dithiol-3-one (HR45)

A. G. Ekström, V. Kelly, J. Marles-Wright, S. L. Cockroft, D. J. Campopiano*. Org. Biomol. Chem. 15, 6310–6313 (2017). Citations

Defocused imaging of UV-driven surface-bound molecular motors
33. Defocused imaging of UV-driven surface-bound molecular motors

B. Krajnik, J. Chen, M. A. Watson, S. L. Cockroft, B. L. Feringa*, J. C. Hofkens*. J. Am. Chem. Soc., 139 (21), 7156–7159 (2017). Citations

H-bond cooperativity
32. Strong short-range cooperativity in H-bond chains

N. Dominelli-Whiteley, J. J. Brown, K. B. Muchowska, I. K. Mati, C. Adam, T. A. Hubbard, A. Elmi, A. J. Brown, I. A. W. Bell, S. L. Cockroft*. Angew. Chem. Int. Ed., 56 (26), 7658–7662 (2017). Citations

Membrane Messengers


30. Transmembrane signalling: Membrane messengers

S. L. Cockroft*. Nature Chem., 9 (5), 406–407 (2017). Citations

The limit of intramolecular H-bonding
29. The limit of intramolecular H-bonding

T. A. Hubbard, A. J. Brown, I. A. W. Bell, S. L. Cockroft*. J. Am. Chem. Soc., 138 (46), 15114–15117 (2016). Citations

-Featured in top ten "most read" articles in J. Am. Chem. Soc. Nov '16 to Jan '17

Molecular machines: membrane bound
28. Man-made molecular machines: membrane bound

M. A. Watson, S. L. Cockroft*. Chem. Soc. Rev., 45, 6118–6129 (2016). Citations

-Featured as a Hot Article in ChemSocRev
-Featured in: ChemSocRev Emerging Investigators 2016 themed collection

Length-dependent formation of transmembrane pores by 3<sub>10</sub> helical aminoisobutyric acid foldamers

27. Length-dependent formation of transmembrane pores by 310 helical aminoisobutyric acid foldamers

J. E. Jones, V. Diemer, C. Adam, J. Raftery, R. E. Ruscoe, J. Sengel, M. I. Wallace, A. Bader, S. L. Cockroft, J. Clayden*, S. J. Webb*. J. Am. Chem. Soc., 138 (2), 688–695 (2016). Citations

An autonomously reciprocating transmembrane nanoactuator

26. An autonomously reciprocating transmembrane nanoactuator

M. A. Watson, S. L. Cockroft*. Angew. Chem. Int. Ed., 55 (4), 1345–1349 (2016). Citations

-Featured as a Hot Paper in Angew. Chem. Int. Ed.

Can dispersion forces govern aromatic stacking in an organic solvent?
25. Can dispersion forces govern aromatic stacking in an organic solvent?

L. Yang, J. B. Brazier, T. A. Hubbard, D. M. Rogers, S. L. Cockroft*. Angew. Chem. Int. Ed., 55 (3), 912–916 (2016). Citations

-Highlighted in Chemistry Views

Quantifying solvophobic effects in non-polar cohesive interactions

24. Quantifying solvophobic effects in non-polar cohesive interactions

L. Yang, C. Adam, S. L. Cockroft*. J. Am. Chem. Soc., 137 (32), 10084–7 (2015). Citations

DNA modulates solvent isotope effects in a nanopore


23. DNA modulates solvent isotope effects in a nanopore

M. A. Watson, S. L. Cockroft*. Chem. Commun., 51, 12243–6 (2015). Citations

Partitioning solvophobic and dispersion forces in alkyl and perfluoroalkyl cohesion

22. Partitioning solvophobic and dispersion forces in alkyl and perfluoroalkyl cohesion

C. Adam, L. Yang, S. L. Cockroft*. Angew. Chem. Int. Ed., 54 (4), 1164–7 (2015). Citations

Can non-polar hydrogen atoms accept hydrogen bonds?
21. Can non-polar hydrogen atoms accept hydrogen bonds?

L. Yang, T. A. Hubbard,S. L. Cockroft*. Chem. Commun., 50 (40), 5212–5214 (2014). Citations

-Featured in: ChemComm Emerging Investigators 2014 themed collection

Seeing through solvent effects using molecular balances

18. Seeing through solvent effects using molecular balances

I. K. Mati, C. Adam, S. L. Cockroft*. Chem. Sci., 4, 3965-72 (2013). Citations

Electrostatic modulation of aromatic rings via explicit solvation of substituents

17. Electrostatic modulation of aromatic rings via explicit solvation of substituents

K. B. Muchowska, C. Adam, I. K. Mati, S. L. Cockroft*. J. Am. Chem. Soc., 135, 9976-79 (2013). Citations

Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures
15. Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures

C. Naughton, N. Avlonitis, S. Corless, J. G. Prendergast, I. K. Mati, P. P. Eijk, S. L. Cockroft, M. Bradley, B. Ylstra, N. Gilbert*. Nature Struct. Mol. Biol., 20, 387-95 (2013). Citations

-Featured in: Nature Struct. Mol. Biol. News & Views

Palladium(II)-mediated assembly of biotinylated ion channels

14. Palladium(II)-mediated assembly of biotinylated ion channels

C. P. Wilson, C. Boglio, L. Ma, S. L. Cockroft, S. J. Webb*. Chem. Eur. J., 17, 3465-73 (2011). Citations

Real-time monitoring of DNA polymerase function and stepwise single-nucleotide DNA strand translocation through a protein nanopore
13. Real-time monitoring of DNA polymerase function and stepwise single-nucleotide DNA strand translocation through a protein nanopore

J. Chu, M González-López, S. L. Cockroft, M. Amorin, M. R. Ghadiri*. Angew. Chem. Int. Ed., 49, 10106-9 (2010). Citations

-Featured in: Chemistry World | Nano Today

Molecular balances for quantifying non-covalent interactions

12. Molecular balances for quantifying non-covalent interactions

I. K. Mati, S. L. Cockroft*. Chem. Soc. Rev., 39, 4195-205 (2010). Citations

Biological nanopores for single-molecule biophysic

11. Biological nanopores for single-molecule biophysics

L. Ma, S. L. Cockroft*. ChemBioChem, 11, 25-34 (2010). Citations

Desolvation and substituent effects in edge-to-face aromatic interactions

10. Desolvation and substituent effects in edge-to-face aromatic interactions

S. L. Cockroft*, C. A. Hunter*. Chem. Commun., 3961-3 (2009). Citations

A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution
9. A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution

S. L. Cockroft, J. Chu, M. Amorin, M. R. Ghadiri*. J. Am. Chem. Soc., 130, 818-20 (2008). Citations

-Featured in: Nature | Nature Nanotechnology | ACS Chemical Biology

Modular multi-level circuits from immobilized DNA-based logic gates
8. Modular multi-level circuits from immobilized DNA-based logic gates

B. M. Frezza, S. L. Cockroft, M. R. Ghadiri*. J. Am. Chem. Soc., 129, 14875-9 (2007). Citations

-Featured in: Nature

Substituent effects on aromatic stacking interactions

7. Substituent effects on aromatic stacking interactions

S. L. Cockroft, J. Perkins, C. Zonta, H. Adams, S. E. Spey, C. M. R. Low, J. G. Vinter, K. R. Lawson, C. J. Urch, C. A. Hunter*. Org. Biomol. Chem., 5, 1062-80 (2007). Citations

Chemical double-mutant cycles: Dissecting non-covalent interactions

6. Chemical double-mutant cycles: Dissecting non-covalent interactions

S. L. Cockroft, C. A. Hunter*. Chem. Soc. Rev., 36, 172-88 (2007). Citations

-Featured in: Supramolecular Chemistry Collection

Desolvation tips the balance: Solvent effects on aromatic interactions - Cover

5. Desolvation tips the balance: Solvent effects on aromatic interactions

S. L. Cockroft, C. A. Hunter*. Chem. Commun., 36, 3806-8 (2006). Citations

Electrostatic control of aromatic stacking interactions

4. Electrostatic control of aromatic stacking interactions

S. L. Cockroft, C. A. Hunter*, K. R. Lawson, J. Perkins, C. J. Urch. J. Am. Chem. Soc., 127, 8594-5 (2005). Citations

Experimental measurement of noncovalent interactions between halogens and aromatic rings

3. Experimental measurement of noncovalent interactions between halogens and aromatic rings

H. Adams, S. L. Cockroft, C. Guardigli, C. A. Hunter*, K. R. Lawson, J. Perkins, S. E. Spey, C. J. Urch, R. Ford. ChemBioChem, 5, 657-65 (2004). Citations

A <sup>1</sup>H NMR study of crystal nucleation in solution

2. A 1H NMR study of crystal nucleation in solution

A. Spitaleri, C. A. Hunter*, J. F. McCabe, M. J. Packer, S. L. Cockroft. CrystEngComm, 6, 489-493 (2004). Citations

Other Published Contributions

Chemistry World

Commentary: Nanomachines can bore cancer cells to death
J. Urquart* Chemistry World, (2017).

book review

Book review: Non-Covalent Interactions in the Synthesis and Design of New Compounds
S. L. Cockroft* Appl. Organometal. Chem., DOI: 10.1002/aoc.3872 (2017).

new type of H-bond

Commentary: New type of hydrogen bond discovered
D. Bradley* Chemistry World, (2016).

silver-pi

Commentary: The silvery life of pi
D. Bradley* Chemistry Views, DOI: 10.1002/chemv.201500052 (2015).

Pd channels

Commentary: An open and shut case for palladium
L. Howes* Chem. Biol. (RSC) 3(9) B66 (2008).