HOME publications Fly passengers Image gallery Contact ICMB Structure/function of chromosome passengers

Survivin papers

1. Human survivin is a kinetochore-associated passenger protein.
Skoufias DA, Mollinari C, Lacroix FB, Margolis RL.
J Cell Biol. 2000 Dec 25;151(7):1575-82.

2. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype.
Uren AG, Wong L, Pakusch M, Fowler KJ, Burrows FJ, Vaux DL, Choo KH.
Curr Biol 2000 Nov 2;10(21):1319-28

3. The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affectchromosomes and the spindle midzone.
Speliotes EK, Uren A, Vaux D, Horvitz HR.
Mol Cell. 2000 Aug;6(2):211-23.

4. Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast.
Li F, Flanary PL, Altieri DC, Dohlman HG.
J Biol Chem. 2000 Mar 10;275(10):6707-11.

5. Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesisand anchorage-independent growth.
Chen J, Wu W, Tahir SK, Kroeger PE, Rosenberg SH, Cowsert LM, Bennett F, Krajewski S, KrajewskaM, Welsh K, Reed JC, Ng SC.
Neoplasia. 2000 May-Jun;2(3):235-41.

6.Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helicalextensions.
Chantalat L, Skoufias DA, Kleman JP, Jung B, Dideberg O, Margolis RL.
Mol Cell. 2000 Jul;6(1):183-9.

7. BIRinging chromosomes through cell division--and survivin' the experience.
Reed JC, Bischoff JR.
Cell. 2000 Sep 1;102(5):545-8. Review.

8 .Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin.
O'Connor DS, Grossman D, Plescia J, Li F, Zhang H, Villa A, Tognin S, Marchisio PC,Altieri DC
Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13103-7.

9. The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner.
Zhao J, Tenev T, Martins LM, Downward J, Lemoine NR.
J Cell Sci. 2000 Dec;113 Pt 23:4363-71.

10. Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin.
Muchmore SW, Chen J, Jakob C, Zakula D, Matayoshi ED, Wu W, Zhang H, Li F, Ng SC, Altieri DC.
Mol Cell 2000 Jul;6(1):173-82

11. Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement.
Verdecia MA, Huang H, Dutil E, Kaiser DA, Hunter T, Noel JP.
Nat Struct Biol 2000 Jul;7(7):602-8

12. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function.
Li F, Ackermann EJ, Bennett CF, Rothermel AL, Plescia J, Tognin S, Villa A, Marchisio PC, Altieri
Nat Cell Biol. 1999 Dec;1(8):461-6.

13. Survivin' cell-separation anxiety.
Reed JC, Reed SI.
Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10170-5.

15.An exegesis of IAPs: salvation and surprises from BIR motifs.
Miller LK.
Curr Biol. 1999 Mar 25;9(6):292-301.

17. Escaping cell death: survival proteins in cancer.
Jaattela M.
Nature. 1998 Dec 10;396(6711):580-4.

19. Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting.
Ambrosini G, Adida C, Sirugo G, Altieri DC.
J Biol Chem. 1998 May 1;273(18):11177-82.

20. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma.
Ambrosini G, Adida C, Altieri DC.
Nat Med. 1997 Aug;3(8):917-21.