people publications research teaching jobs
contact publications research teaching opportunities

2012


42. Tildesley, M. J., Gally, D. L., McNeilly, T. N., Low, J. C., Mahajan, A., and Savill, N. J., 2012. Insights into mucosal innate responses to Escherichia coli O157:H7 colonization of cattle by mathematical modeling of excretion dynamics. J. Roy. Soc. Interface 9, 518-527.


2011

41. Atkins, K. E., Read, A. F., Savill, N. J., Renz, K. G., Walkden-Brown, S. W. and Woolhouse, M. E. J., 2011. Modelling Marek's diesase virus (MDV) infection: parameter estimates for mortaility rate and infectiousness. BMC Vet. Res. 7, Art. No. 70.

40. Mideo, N., Savill, N. J., Chadwick, W., Schneider, P., Read, A. F., Day, T. and Reece, S. E., 2011. Causes of variation in malaria infection dynamics: insights from theory and data. Am. Nat. 178, 174-188.

39. Mitchell, K. M., Mutapi, F., Savill, N. J. and Woolhouse, M. E. J., 2011. Explaining observed infection and antibody age-profiles in populations with urogenital schistosomiasis. PLoS Comp. Biol. 7, Art. No. e10002237.

38. MacGregor, P., Savill, N. J., Hall, D., Matthews, K. R., 2011. Transmission Stages Dominate Trypanosome Within-Host Dynamics during Chronic Infections. Cell, Host & Microbe 9, 310-318.


37. Volkova, V. V., Bessell, P. R., Woolhouse, M. E. J. and Savill, N. J., 2011. Evaluation of risks of foot-and-mouth disease in Scotland to assist with decision making during the 2007 outbreak in the UK. Vet. Rec. 169, 124-127.

2010

36. Singh, B. K., Savill, N. J., Ferguson, N. M., Robertson, C. and Woolhouse M. E. J., 2010. Rapid detection of pandemic influenza in the presence of seasonal influenza. BMC Public Health 10, 726-736.

35. Zhang, X. S., Chase-Topping, M. E., McKendrick, I. J., Savill, N. J. and Woolhouse, M. E. J. 2010. Spread of E. coli O157 infection among Scottish cattle farms: Stochastic models and model selection. Epidemics 2, 11-20.

34. Miller, M. R., Raberg, L., Read, A. F. and Savill, N. J. 2010.  Quantitative analysis of immune response and erythropoiesis during rodent malaria infection, PLoS Comp. Biol, 6(9):e1000946.

33. Bessell, P. R., Shaw, D. J., Savill, N. J. and Woolhouse, M. E. J. 2010.  Estimating risk factors for farm-level transmission of disease: Foot and mouth disease during the 2001 epidemic in Great Britain, Epidemics 2, 109-115.

32. Volkova, V. V., Howey, R., Savill, N. J. and Woolhouse, M. E. J. 2010. Potential for transmission of infections in networks of cattle farms, Epidemics 2, 116-122.

31. Volkova, V. V., Howey, R., Savill, N. J. and Woolhouse, M. E. J. 2010. Sheep movement networks and the transmission of infectious diseases, PloS ONE 5, e11185.

30. Bessell, P. R., Shaw, D. J., Savill, N. J. and Woolhouse, M. E. J. 2010. Statistical modelling of holding level susceptibility to infection during the UK 2001 Foot and Mouth Disease epidemic, Int. J. Infect. Dis. 14, E210-E215.

29. Deardon, R.,
Brooks, S. P., Grenfell, B. T., Keeling, M. J., Tildesley, M. J., Savill, N. J., Shaw, D. J., Woolhouse, M. E. J., 2010, Inference for individual-level models of infectious diseases in large populations, Statistica Sinica, 20, 239-261.

2009

28. Howey, R., Quan, M., Savill, N. J., Matthews, L., Soren, S. and Woolhouse, M. E. J., 2009, Effect if initial dose of foot-and-mouth disease virus on the early viral dynamics within pigs, J. Roy. Soc. Interface, 6, 835-847.

27. Savill, N. J., Chadwick, W. and Reece, S. R., 2009, Quantitative analysis of mechanisms that govern red blood cell age structure and dynamics during anaemia, PloS Comput. Biol, 5(6): e1000416.

2008

26. Mideo, N., Barclay, V. C., Chan, B. H. K., Savill, N. J., Read, A. F. and Day, T., 2008, Understanding and predicting strain-specific patterns of pathogenesis in the rodent malaria Plasmodium chabaudi, Am. Nat, 172, E214-E238.

25. Bessell, P. R., Shaw, D. J., Savill, N. J., and Woolhouse, M. E. J., 2008, Geographic and topographic determinants of local FMD transmission applied to the 2001 UK FMD epidemic, BMC Vet. Res, 4:40.

24. Savill, N. J., St. Rose, S. G. and Woolhouse, M. E. J., 2008, Detection of mortality clusters associated with highly pathogenic avian influenza in poultry: a theoretical analysis, J. Roy. Soc. Interface, 5, 1409-1419.

23. Tildesley, M. J., Deardon, R., Savill, N. J., Bessell, P. R., Brooks, S. P., Woolhouse, M. E. J., Grenfell, B. T. and Keeling, M. J., 2008, Accuracy of models for the 2001 foot-and-mouth epidemic, Proc. Roy. Soc. Lond. B, 275, 1459-1468.

22. Woolhouse, M. E. J., Howey, R., Gaunt, E., Reilly, L., Chase-Topping, M. and Savill N., 2008, Temporal trends in the discovery of human viruses, Proc. Roy. Soc. Lond. B, 275, 2111-2115

2007

21. Liu, W., Matthews, L. Chase-Topping, M., Savill, N. J., Shaw, D. J. and Woolhouse, M. E. J., 2007,  Metapopulation dynamics of Eschericha coli O157 in cattle: an exploratory model, J. Roy. Soc. Interface 4, 917-924.

20. Tildesley, M. J., Savill, N. J., Shaw, D. J., Deardon, R., Brooks, S. P., Woolhouse, M. E. J., Grenfell, B. T. and Keeling, M. J., 2007, Vaccination strategies for foot and mouth disease (reply), Nature 445, E12.

19. Savill, N. J., Shaw, D. J., Deardon, R., Tildesley, M. J., Keeling, M. J., Woolhouse, M. E. J., Brooks, S. P. and Grenfell, B. T., 2007, Effect of data quality on estimates of farm infectiousness trends in the UK 2001 foot-and-mouth disease epidemic, J. Roy. Soc. Interface 4, 235-241.

2006

18. Savill, N. J., St. Rose, S. G., Keeling, M. J., and Woolhouse, M. E. J., 2006, Silent spread of H5N1 in vaccinated poultry, Nature 442, 757. Supplementary material.

17. Savill, N. J., Shaw, D. J., Deardon, R., Tildesley, M. J., Keeling, M. J., Woolhouse, M. E. J., Brooks, S. P. and Grenfell, B. T., 2006, Topographic determinants of foot and mouth disease transmission in the UK 2001 epidemic, BMC Veterinary Research 2:3.


16. Tildesley, M. J., Savill, N. J., Shaw, D. J., Deardon, R., Brooks, S. P., Woolhouse, M. E. J., Grenfell, B. T. and Keeling, M. J., 2006, Optimal reactive vaccination strategies for a foot and mouth outbreak in the UK, Nature 440, 83-86.
Supplementary material.

2004

15. Savill, N. J. and Seed, J. R., 2004, Mathematical and statistical analysis of the Trypanosoma brucei slender to stumpy transformation, Parasitology 128, 53-67.

14. Turner, S., Sherratt, J. A., Painter, K. J. and Savill, N. J., 2004, From a discrete to a continuous model of biological movement, Phys. Rev. E 69, art. no. 021910.

2003

13. Savill, N. J., 2003, Mathematical models of hierarchically structured cell populations under equilibrium with application to the epidermis, Cell Prolif. 36, 1-26.

12. Savill, N. J. and Sherratt, J. A., 2003, Control of epidermal stem cell clusters by Notch-mediated lateral induction, Dev. Biol. 258, 141-153.
Supplementary material.

2002

11. Savill, N. J., Weller, R. and Sherratt, J. A., 2002, Mathematical modelling of nitric oxide regulation of rete peg formation in psoriasis, J. theor. Biol. 214, 1-16.

10. Sherratt, J. A., Weller, R. and Savill N. J., 2002, Modelling blood flow regulation by nitric oxide in psoriatic plaques, Bull. Math. Biol. 64, 623-641.

2001

9. Savill, N. J., Hoyle, D. C. and Higgs, P. G., 2001, RNA sequence evolution with secondary structure constraints: Comparison of substitution rate models using maximum-likelihood methods, Genetics 157, 399-411.

2000

8. Simpson, L., Thiemann, O. H., Savill, N. J., Alfonzo, J. D. and Maslov, D. A., 2000, Evolution of RNA editing in trypanosome mitochondria, P. Natl. Acad. Sci. USA 97, 6986-6993.

7. Savill, N. J. and Higgs, P. G., 2000, Redundant and non-functional guide RNA genes in Trypanosoma brucei are a consequence of multiple genes per minicircle, Gene 256, 245-252.

1999

6. Savill, N. J. and Higgs, P. G., 1999, A theoretical study of random segregation of minicircles in trypanosomatids, Proc. Roy. Soc. Lond. B 266, 611-620.

5. Savill, N. J. and Hogeweg, P., 1999, Competition and dispersal in predator-prey waves, Theo. Pop. Biol. 56, 243-263.

1998

4. Savill, N. J. and Hogeweg, P., 1998, Spatially induced speciation prevents extinction: The evolution of dispersal distance in oscillatory predator-prey models, Proc. Roy. Soc. Lond. B 265, 25-32.

1997

3. Savill, N. J. and Hogeweg, P., 1997, Modelling morphogenesis: From single cells to crawling slugs, J. theor. Biol. 184, 229-235.

2. Savill, N. J. and Hogeweg, P., 1997, Evolutionary stagnation due to pattern-pattern interactions in a co-evolutionary predator-prey model, Artificial Life 3, 81-100.


1. Savill, N. J., Rohani, P. and Hogeweg, P., 1997, Self-reinforcing spatial patterns enslave evolution in a host-parasitoid system, J. theor. Biol. 188, 11-20.

Book chapters

Savill, N. J. and Hogeweg, P., 1997, A cellular automata approach for modelling cell-cell interactions, in Dynamics of Cell and Tissue Motion, Eds. Alt, A., Deutsch, A. and Dunn, G., Birkhäuser Verlag, Basel. pp. 203-208.

Savill, N. J. and Merks, R. M. H., 2007, The cellular potts model in biomedicine, in Single-Cell-Based Models in Biology and Medicine, Eds. Anderson, A. R. A., Chaplain, M. A. J. and Rejniak, K. A., Birkhäuser Verlag, Basel. pp. 137-150.

Reports

Savill, N. J., 1991, Smear studies for the Dynamics Aperture Experiment, CERN SL-AP Note 90-19.

Savill, N. J., St. Rose, S. G., and Woolhouse, M. E. J., 2006, Final Report for Avian Influenza Epidemiological Modelling and Economic Assessment, DEFRA.


Savill, N. J., Volkova, V. and Bessell, P., 2007, Risk Assessment of Introduction and Maintenance on Scottish Agricultural Holdings of Foot and Mouth Disease Virus Responsible for the 2007 Outbreak in England, Scottish Government.

Volkova, V., Savill, N. J., Bessell, P. R. and Woolhouse, M. E. J. 2008. Report on seasonality of movements and spatial distribution of sheep, cattle and pigs in Scotland. Report to Animal Health and Welfare Division of the Scottish Government’s Rural and Environment Research and Analysis Directorate. ISBN 978 0 7559 1718 1.

Volkova, V. and Savill, N. J. (2008). Report on volume of monthly movements of sheep, cattle and pigs off Scottish holdings in 2006, for Animal Health and Welfare Division of RERAD.

Conference Proceedings

Burns, A., Chapmanhatchett, A., Crosetto, D., Herr, W., Hunt, S., Jacob, H., King, Q., Lavender, M., Savill, N., Schmidt, F., Schmidt, R., Sweeney, A. 1990. The BOSC Project, EPAC 90, Volumes 1 and 2: 2nd European Particle Accelerator Conference.